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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2cb2d00a40d92f0a35db14e8a83b30bd1524b0706bbd140c7c315da14bd1f48' 
  AND token = 'PsIN0o798xrYcHZbEZHDdO2bJb9en1DzcleKf8WD338=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}