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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241d6935d33c47ceb35e0d66d6af09e511f54a2536cee10a0f60a8b095b9e4c5' 
  AND token = '1u8xaW6oGS9yP95hNLVt1+FU3O/Cc8Cgf1jcQ34VUUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}