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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebe63f8262274d1f523c01750929729a2c5e03448e8aa7210c4406d8360e210f' 
  AND token = 'uVhsmW3aJANJ+SJD/JFrlSfYs99d2CKYx77cDY59Nm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}