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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb818863ec6f2d361cfe6f50aad5d071cee9fd831e13029de106a672c15ff34' 
  AND token = '3Fd7PnvA8YNZVRn3lSXKciRNzUjREIznxx1XWYFLTXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}