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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b927a66e431509aca67e689ab42f4096074314d85dd1ffa3d1f4a367a9d92c0' 
  AND token = 'qjztDbvFS6XMTCDV64Px1UhdE3iQwL948VT6j2O9z3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}