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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641cbd3286b0094cbce1809ea4228c4e1cfbc3bce8514bb8fcfb2248014e1a7e' 
  AND token = 'trUQtv5HKW7ENCiqJMDG7CFqBYg6/3xjywsumfSypmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}