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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '558f8c169d38fcc793ec5cf007647de9d00b9dea755c248a7eb7fd149e129cca' 
  AND token = '5+Yix34o4oG8hvbH9rbsLrAUdHYxRFM+jNSMhLdf8/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}