SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9db246c381b846f5e6328723a6d883b50a8d25870bb3750b21da90c071a124e' 
  AND token = 'CYnIWPwPTOb+Wia1vWTKA6b4IZvqh+SdNTR06wTU7zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}