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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c7a5112502d98d73cedd5f482b30cff47ee46f3773c1b0b1ac0978df2b3208b' 
  AND token = 'bigo4pNWhbICxyuE9JMklUne+z7uwPpoOMOXtOCatyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}