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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f245a28f83c8dd224029775495e15ae5d31db9fb134ec33940d5495e84e2566' 
  AND token = 'yR3GpyJXA+mz0AZI95AiMcXiAw3DN5zDl5oBQGFkrO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}