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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a657b48c2fe96e56fe10e7e493c0472b8ab20b098f67e01a99f0a71a4ffb4f80' 
  AND token = 'Mk/0PEAFWZXF1Nj31rAEEJ7zDRxy4+7+YYYLBiKsQK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}