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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f592d4797deda37931c89a7209c0b2988f256e2d5fa9ccb8f3fcc74bf9fa2b81' 
  AND token = 'vKVdsC3Ft9CL0JKIDGDrUO/I7dSVirboE/nODz0yn6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}