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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449d39075ab5661faad6ee57441a4de0cd30f80d42cc84ff8a172bfb6041e479' 
  AND token = 'uICbjY+88hCYgrIcDU8aEZrscLxjU59EsuxD2Js+Xeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}