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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d06240399b530421fa57f691b7fd4515eab66276609fdc029c77b16dbc15907' 
  AND token = 'vVQ9h66GObSIq0OsukXJGSZF1i1gPA31A7h4WxSQarg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}