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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8654aa0568fe82f4bcec00c621d73157c381b1811a10375d779e776f3a9d132a' 
  AND token = 'CDOy2cvf6xp9Yz8immYczCYogwYmKEY66cmEKP4CTkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}