SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04cf7fe7b757b136181cc68746d2b0d5b66863a4eddb79773df203e4120fdba2' 
  AND token = '1+8zJFTsmjfhCDMimkn/s4bGyGV0iK3IuSFEeWpIoc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}