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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '633790f1f1a8645b6b2f6405d5cea645b2e418ab66dd880bed8ef9edee5813e2' 
  AND token = 'ECF47ByOA/A0XCZX82DVK8TlkHOw+HA2Vc+0/hZhtUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}