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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e65058f1d92e6f9fd2436a8fe639b5a3177fe8ca065ce1e044674674dbb5438' 
  AND token = 'Dp99kaxoNzdHttD4hBTkJGCcniqkEG9O23gi4e/SjtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}