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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b650e1d4d7ef5dc4107e3e81e298dc748ea409a96acb607c5e1ec3e1387fdf66' 
  AND token = 'AkWUkK9K/Jmu6Gk9+oBgpzB7MGxRcVlc1aFSfzcY+RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}