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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae5e9aa09529778941cabb0526871cb5321862a639d7939b5daa32157a9c0a4a' 
  AND token = 'EmEB1t6ITidBreCvlDfz9PJ2hBwDO+AKcC8bb4fkNKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}