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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35325064f80e6aeda678702b7f6b6db1daa059fdbe62e45a3844f7ce9968c896' 
  AND token = '2rc3KjMOvaLy4mIJzNUV63/b12l4ryPifLr4GkLsLNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}