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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '166cee6b27789285939861298a425c873b6ab28e72e077aae8e9145f066bbe67' 
  AND token = 'w8NZIFJa1pLwjlDcYRpoWIiVBfOjekvrEx1HsPmhA4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}