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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7d210f156ff2539c84f2b3a6efd2e097e4af03ede0999e0577467f1b1866c6' 
  AND token = 'eGWeBYt3W99oDpt233vKTF88MUWQV4AXlwNxRv95YLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}