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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159adc92c40ef8766ed6342914b8a16172bbe2af7269231c6a4b53a7d278b1c5' 
  AND token = 'WH0D9bjM5s8oQGxkQLfHkx/k0cC2Nz1YzHxHOSYx37s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}