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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eb2a69f32cc6c7a4c3a98d3685c27ff70a597f31957c5ea31238651ec3086c6' 
  AND token = 'D7ncSrmNat4MCdQs4pD2NHNjOesCFwVG7yBeTb2jPYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}