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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace8bc14d7a5c54e343f9cb55fe9183159214987becec92b8f19a61a5329385d' 
  AND token = '7zaeI0/vjN6HxTn/PRtxzgMiA/MYRkoPluMfjaH/LYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}