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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7829d37b6978a08428157b1c425c2834e22f74bffb70e82ddd21fc03d5c6904e' 
  AND token = 'UMddhM1uccnLNYEf57jSZgnrB/stV0sD7nNl0R/zt3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}