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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b3646fb5fa777abf54d7775f2653264c2b586a9c605f5e4d85dcb6014f83626' 
  AND token = 'D467rU1uBJAn864PcWHlYrh2H0j2/wQ8GygsiM8bChg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}