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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1351cc52d2483e5230c529db826720e2893e518527668aaa929ee15c5b69600a' 
  AND token = 'OFqfxFltNN/WVAuqGWBuCDSX+cx4OMkvVn7Cm4uK6YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}