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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4d52bee6cc48f46df31ef97715b2b04e561c185d1cb2d8687870a515a367f0' 
  AND token = 'bC32Nvo3pqA9oMdCKbsMRuQUxwSE3/v+QWywB3+uBbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}