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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e7d3620fc87baa5a1af96a9b848741d5af9d16dc2e548d95cfcd2c5a22fdef' 
  AND token = 'WzdatpLEsm8g7IEPCBonQ+DRsV3U+iSIcuDd/HDyr5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}