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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53900e8c95628d5c7ccda82a23b3e27a7bcc6e214c07a6204a501e0f49ee5c3a' 
  AND token = 'P4trxsDlq9yuSkBzHRV6iPX5SvbGs5L9xsHHX69s3bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}