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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f945643fcb6714655303f0e7468db88833ed46becc74804166821838c4c1bd9d' 
  AND token = 'd3cUaHpBkq0+mT4KGTA/qfM3BbGD/B+6OcISaSQY58g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}