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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ca5b768682c8deb30d51baa56ae07064e224380f8105d5190efaada3ee2daab' 
  AND token = 'eF/NXM3M4YoII5gJrE/xdhSYB4ePWiiLDxzIFWvLvgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}