SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1ebdf615ec49c8cc3421667f60d124af3340b104c1eab3426dec86bcddcae8' 
  AND token = 'veHeDA7lXYd1JHP0WzaZTDa2nVWLPavbCeWaPGA0ER4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}