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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1880d1ce3bd41dffa512f45d65dc4492d8df3d217815b20d673b4a56e866372c' 
  AND token = 'OGlAuas7Pl0UrwOlqO8Ca4i1h+/RmLv6io0+BZk/oqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}