SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27f9fc39d221fd6babaa5665c97e5138e05669988f7c0f2f77019701a6a7c791' 
  AND token = 'I9ZjuigwcL1EafVWBnXcwcwd3lhMdktNaRtyz+GnYh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}