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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c02a6d1d764e527d15144d2fc2c48645c1bd5175e789946a95bb94af566b15' 
  AND token = 'o/VfFicag54VSgEO10jd3sCGvJ4Af3A0z5+YbPRQ3s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}