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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6a3e04a78b2eb2b9be1645bdacc7b31eb22697028607e4f6721fdbb14ff3aa' 
  AND token = 'plhf/IkIVx8MJ4CPp1mWozLL0loWRO/FxgAWe9gHhDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}