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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8298c49af433e884f62ed6e186df9ad6b33f2211e1c09c43214321f1c7c1c494' 
  AND token = 'hxbJtAmm8MXALnU1UGm4sE2vx6mk2XPdsznkOMx4OVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}