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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273008654512d1302c351122e885689ce62f83e98446e9fee3194f134d5d258b' 
  AND token = 'YDbjxdF1n4YjXq06fBT298zxYeyxBGFSSlCpIXuM4Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}