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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c29b3023e6422a5d5cdcaf0d6c7ebf9e3929177fb67c628c850fecd158debf25' 
  AND token = 'AXYK+joj6Zd788OH78AvOHiK49Tjb6G2GuIaLt2vp84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}