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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a95bbbc0c60d965f818d114a0f437c6f9eb746b2e66319a1f513518626ff48' 
  AND token = 'mk3lybKG4Q7fJowpmF4e7XOUj0myLUNn5qtFN6vh0K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}