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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e54640d7b6851ddc2ec86cbc4aef835305c8ab635f24b63d4544ddccfbb7cf2' 
  AND token = 'UjyY6Uq/uDEbvlN1mUBCLRioMdGIsL8hWdCX+Y6gjfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}