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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7f604d99e00428b29bfd7e3c8b8b53e33edcbfd6001e39400d72b8550e9ac0d' 
  AND token = 'aNPeY/wv8UhDxU/ZfLNjynoX34A7Jqcx2d4ubNR7yhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}