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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2e9f8913c5e2e26faeaf74e0b1b8510a5e8aa5a1e79894c489433056c42b19' 
  AND token = 'eZsM/gIpCGmqFl9A/6cbwxmOz86/3FqedZ1GIKREGCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}