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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b8496984ad9d948ebe33af1732e9f9307bdc77a7ad549143556d46dd291398' 
  AND token = 'ALTpWWO0KwZk9jJ833iOC9l1PPoC+/1YPrBA1P5f/ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}