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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eb87049ccd61927955461b407e7f527f964baec3ec6ce376fd244129b4cffc2' 
  AND token = 'MW0Un40PbcpWBUTgKBWsTaod7kZ9VluvhDCnWNIL/eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}