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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deb9e353edbfe4e0a72a99587d324178f3cd5373ff4d512b15fc2beb710b9133' 
  AND token = '0q5UBc/JW5C+CAD3n91o450bN2P57TMUsTltvieQ5mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}