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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2035e94223dc626e94d06eb1fbd2043ad39b2c48ac96853a14b835f0dcba4af0' 
  AND token = 'oNkkfxrvDBiWCY2sspTLQ/sH8jddBuoL0XxwlajYM/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}